Left-Handed Sugar

In nature, molecules are chiral—they turn in one direction or the other. Naturally then, someone wondered: might sugar, built to mirror itself, be sweet, but pass through the body unnoticed? A dieters’ gold mine. I don’t know why the experiment failed, or how. I think of the loneliness of that man-made substance, like a ghost in a ‘50s movie you could pass your hand through, or some suitor always rejected despite the sparkle of his cubic zirconia ring. Yet this sugar is real, and somewhere exists. It looks for a left-handed tongue.

—2009

Originally published in Come, Thief  (Knopf, 2011); all rights reserved. Copyright © by Jane Hirshfield. Reprinted with the permission of the author.